If a mother or father on the proband is known to hold the pathogenic variant discovered in the proband, the danger towards the sibs of inheriting the pathogenic variant is 50%. Due to decreased penetrance, sibs who inherit the pathogenic variant may or may not create aHUS (see Penetrance). Their https://airhandlingunitahuhire87520.activablog.com/31238716/the-single-best-strategy-to-use-for-ahu-s