Conolidine’s analgesic results stem from its conversation with non-opioid pain pathways. Contrary to opioids, which bind to µ-opioid receptors from the central nervous system, conolidine modulates alternate molecular targets. A Science Advances analyze observed that conolidine interacts Together with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabil... https://conolidine96958.activablog.com/36993293/alternative-natural-pain-relief-to-replace-traditional-painkillers-an-overview